Prolia is indicated to treat osteoporosis in postmenopausal women that are at a high risk of bone fracture and glucocorticoid-induced osteoporosis in men and women at a high risk for bone fracture. It is also indicated to increase bone mass in men with osteoporosis at high risk for fracture, increase bone mass in men that are at high risk for fracture and are receiving androgen deprivation treatment for nonmetastatic prostate cancer, and to increase bone mass in women that are at a high risk for fracture and are receiving adjuvant aromatase inhibitor treatment for breast cancer. Postmenopausal women are at risk of developing osteoporosis, as their bone mineral density rapidly decreases with the loss of estrogen as they undergo menopause. Patients receiving Prolia need to take calcium and vitamin D supplements.
Prolia has been shown to effectively helps increase bone density. Patients on Prolia follow a convenient dosing schedule of one injection every six months, which encourages compliance.