RESTYLANE® DEFYNE™ with Lidocaine is a hyaluronic acid (HA) dermal filler designed for the treatment of deep dynamic wrinkles and folds. Formulated using XpresHAn Technology™, it provides resilient structure and flexibility, allowing the filler to comfortably adapt to natural facial movement while maintaining support in expression-rich areas. 0.3% lidocaine is included to enhance comfort during injection.

Key Benefits

• Smooths deep nasolabial folds and marionette lines

• Maintains natural facial movement with resilient flexibility

• Strong structural support for expression-driven areas

• Hydrating HA helps improve skin texture and smoothness

• Includes lidocaine for a more comfortable treatment experience

How It Works
The XpresHAn Technology™ cross-linking process creates a gel with both elasticity and support, helping keep deep wrinkles softened even during active facial expressions — without a stiff or “frozen” look.

Ideal Candidates

• Adults seeking correction of deeper lines including:
  • Nasolabial folds
  • Marionette lines
  • Lower facial contour concerns

• Patients who want strong correction with natural expression preserved

Administration

• Supplied as a sterile pre-filled syringe, single-use

• Injected into the mid-to-deep dermis depending on severity of folds

• Only to be administered by trained medical professionals

• Immediate results with continued refinement as product integrates

Possible Side Effects

• Temporary swelling or redness at injection sites

• Mild tenderness, bruising, or firmness

• Rare inflammatory or hypersensitivity reactions