ORTHOVISC® is a sterile, non-pyrogenic, viscoelastic hyaluronan solution used to treat knee osteoarthritis pain in patients who have not achieved sufficient relief from conservative measures including exercise, physiotherapy, or oral pain medications. Each pre-filled syringe contains 15 mg of highly purified hyaluronan in 2 mL, sourced from a non-avian, bio-fermented process to ensure high quality and reduced risk of sensitivity reactions.

By supplementing the natural hyaluronic acid in synovial fluid, ORTHOVISC® helps restore cushioning, lubrication, and normal joint biomechanics — improving mobility and reducing discomfort.

Key Benefits

• Effective non-surgical treatment for knee osteoarthritis pain

• Improves lubrication and shock absorption within the joint

• Non-avian derived hyaluronan — lower allergenic potential

• Supports improved function and daily movement

• Suitable for a wide range of patients

Administration

• Provided as a single-use pre-filled syringe (2 mL)

• Typically administered as one injection per week over a 3–4 week course

• For intra-articular use only and must be administered by a trained healthcare professional

How It Works
ORTHOVISC® enhances the viscoelastic properties of the synovial fluid, helping protect the cartilage and reduce friction during movement. Clinical benefits may increase across the treatment course and continue after completion.

Ideal Candidates

• Adults with knee osteoarthritis seeking non-opioid pain management

• Patients unable to tolerate or unresponsive to traditional analgesics

• Individuals aiming to delay or avoid surgical intervention

Possible Side Effects

• Temporary joint swelling or discomfort

• Mild localized redness, warmth, or stiffness

• Rare allergic or inflammatory reactions