CIMZIA® is a prescription biologic medication used to manage chronic autoimmune and inflammatory conditions by selectively blocking tumour necrosis factor-alpha (TNF-α). Each pre-filled syringe contains 200 mg of certolizumab pegol in 1 mL, allowing flexibility for both loading and maintenance dosing regimens. This pack includes two pre-filled syringes for clinician-directed administration.

Key Features & Indications

• Effective for adults with:
  • Moderate to severe rheumatoid arthritis
  • Active psoriatic arthritis
  • Ankylosing spondylitis
  • Non-radiographic axial spondyloarthritis
  • Moderate to severe plaque psoriasis
  • Moderately to severely active Crohn’s disease with inadequate response to conventional therapy

• Helps reduce inflammation, relieve symptoms, and improve mobility and quality of life

• Subcutaneous administration for controlled dosing

• PEGylated formulation designed for extended activity in the body

How It Works
CIMZIA® neutralizes TNF-α, a key inflammatory cytokine involved in joint, skin, and gastrointestinal tissue damage. By suppressing abnormal inflammation, it helps preserve joint structure, support skin clearance, and reduce disease activity in chronic autoimmune disorders.

Ideal Candidates

• Patients with diagnosed autoimmune conditions requiring biologic therapy

• Individuals who have not responded sufficiently to other disease-modifying treatments

• Suitable for long-term management under the care of a specialist

Possible Side Effects & Considerations

• Increased risk of infections due to immune modulation — screening and monitoring recommended

• Injection-site reactions, respiratory infections, headaches or rash may occur

• Rare risks include malignancies and serious immune-related events

• Live vaccines should generally be avoided during therapy

• Must be clinically evaluated and monitored before and during treatment

Administration & Packaging

• Each syringe: 200 mg certolizumab pegol / 1 mL solution

• Pack format: 2 pre-filled syringes

• For subcutaneous use by trained healthcare professionals

• Typically stored refrigerated until use